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Valproate-induced Gingival Overgrowth : A Case Report

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¼ÛÁöÇý ( Song Ji-Hyeo ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
ÀÌ°íÀº ( Lee Ko-Eun ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
½Å¹Î°æ ( Shin Min-Kyung ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
±è¼º¿À ( Kim Seong-Oh ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
ÃÖº´Àç ( Choi Byung-Jai ) - Yonsei University College of Dentistry Department of Pediatric Dentistry
ÃÖÇüÁØ ( Choi Hyung-Jun ) - Yonsei University College of Dentistry Department of Pediatric Dentistry

Abstract


Drug-induced gingival overgrowth is an abnormal increase of gingival tissues caused as a side effect of systemic medication. This report presents a severe case of valproate-induced gingival overgrowth combined with ulcerative and hemorrhagic lesions in a patient with Lennox-Gastaut syndrome. Considering the patient¡¯s limited cooperative ability, gingivectomy and excisional biopsy under general anesthesia were performed. The lesions were successfully treated without recurrence. When gingival enlargement does not subside with nonsurgical treatments, surgical procedure and excisional biopsy are to be performed. Postoperative management of oral hygiene is critical to prevent recurrence.

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Drug-induced gingival overgrowth; Valproate; Lennox-Gastaut syndrome; Gingivectomy

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